Axillary odor can seriously compromise a person's quality of life. In previous posters,
we have shown that the effectiveness of hygiene measures for controlling odor were
enhanced following application of either a deodorant or antiperspirant (AP) preparation.
The current poster presents the antiodor results of a direct clinical comparison between
a perfume-free AP product containing aluminum zirconium trichlorohydrex glycine (IZAG)
and a perfume-free glycol-based deodorant product containing triclosan. The clinical
trial was conducted at the Hill Top Research Center (Loveland, Ohio). In the study
53 male volunteers completed a 12-day conditioning period in which they did not use
a deodorant or AP product. At the end of this period, subjects were entered into the
5-day treatment phase if 24 hours after a controlled soap wash they received an axillary
odor score of 4 or higher (0-10 scale). For the product comparison, subjects received
0.4 g of the glycol-based deodorant on one axilla and 0.4 g of the AP product on the
other axilla. Product was applied daily to each axilla using a controlled application
procedure. Odor scores were obtained at baseline, and at 12 and 24 hours after the
first, third, and fifth day's treatment.
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© 2005 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.