Evaluation of oral zinc sulfate effect on recalcitrant multiple viral warts: A randomized placebo-controlled clinical trial

      To the Editor: Viral warts are caused by the human papillomavirus (HPV).
      • Gibbs S.
      • Harvey I.
      • Sterling J.
      • Stark J.
      Local treatment for cutaneous warts: systemic review.
      • Al-Gurairi F.T.
      • Al-Waiz M.
      • Sharquie K.E.
      Oral zinc sulfate in the treatment of recalciterant viral warts: randomized placebo-controlled clinical trial.
      Because HPV infection is nonlytic, antigen presentation occurs very slowly. HPV infection does not induce inflammatory cytokines; therefore, therapeutic options aimed at modulating the immune system and facilitating the production of cytokines have been proposed.
      • Parton A.M.
      • Sommerville R.G.
      The treatment of plantar verrucae by triggering cell-mediated immunity.
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