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A comparison of sunburn protection of high–sun protection factor (SPF) sunscreens: SPF 85 sunscreen is significantly more protective than SPF 50

      To the Editor: On August 27, 2007, the US Food and Drug Administration (FDA) released a proposed amendment to the 1999 sunscreen monograph. An important aspect of this amendment is that the FDA has proposed that manufacturers label their products with a specific sun protection factor (SPF) value up to 50; sunscreens with SPFs >50 would be labeled as 50+. We conducted a double-blind, randomized, split-face clinical study to evaluate whether a statistically significant difference exists between the sunburn protective effects of a SPF 50 sunscreen versus a SPF 85 formulation.
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