Probiotics and prebiotics in dermatology

      The rapid increase in the medical use of probiotics and prebiotics in recent years has confirmed their excellent safety profile. As immune modulators, they have been used in inflammatory skin conditions, such as atopic dermatitis. We review the literature regarding the use of probiotics and prebiotics in dermatology. Probiotics and prebiotics appear to be effective in reducing the incidence of atopic dermatitis in infants, but their role in atopic dermatitis treatment is controversial. Their role in acne, wound healing, and photoprotection is promising, but larger trials are needed before a final recommendation can be made.

      Key words

      Abbreviations used:

      AD ( atopic dermatitis), CDAD ( Clostridium difficile–associated diarrhea), IFN-γ ( interferon gamma), OR ( odds ratio), PAD ( pediatric atopic dermatitis), RR ( relative risk), SCORAD ( SCORing Atopic Dermatitis)
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