Combination of skin micro-needling and topical application of tranexamic acid and vitamin C: New clinical application: A pilot study for treatment of persistent post acne erythema

        Background: Acne is considered as one of the most common skin disease which has many etiological factors. Many treatment regimens of acne are being used with very successful results. However in the process of healing of the inflammatory lesions, they may leave a post acne erythema, also referred as postinflammatory erythema (PIE), which is defined as lesions of erythematous macules. Postacne erythema lesions may improve with time, or may persist for months and it even may end up by acne scarring. Variables methods of treatment has been tried to treat persistent post acne erythema including topical treatment with retinoids, intensive light therapy (IPL), or pulsed dye laser with variable results of success. Skin micro-needling is a technique which helps to facilitate skin healing and repair. Tranexamic acid (TA) is an antifibrinolytic agent that shows a positive effect on wound healing in several studies and it showed benefits in treating skin diseases like melasma, rosacea erythema and ultraviolet induced pigmentations. Vitamin C, known for its antioxidant properties and its key role in collagen production and skin regeneration.
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