The depth of inflammation in frontal fibrosing alopecia and lichen planopilaris: A potential distinguishing feature

      To the Editor: Primary cicatricial (scarring) alopecias are disorders in which the follicular unit is targeted by inflammation and replaced by fibrosis, leading to permanent hair loss. They are categorized according to the inflammatory cell present.
      • Olsen E.
      • Bergfeld W.
      • Cotsarelis G.
      • et al.
      Summary of North American Hair Research Society (NAHRS)-sponsored workshop on cicatricial alopecia, Duke University Medical Center, February 10 and 11, 2001.
      Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are lymphocytic scarring alopecias that differ clinically, but have identical histologic findings.
      • Kossard S.
      • Lee M.
      • Wilkinson B.
      Postmenopausal frontal fibrosing alopecia: a frontal variant of lichen planopilaris.
      After observing deep perifollicular inflammation in several biopsy specimens of FFA, the authors sought to study the depth of inflammation in LPP and FFA.
      To read this article in full you will need to make a payment
      AAD Member Login
      AAD Members, full access to the journal is a member benefit. Use your society credentials to access all journal content and features
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Olsen E.
        • Bergfeld W.
        • Cotsarelis G.
        • et al.
        Summary of North American Hair Research Society (NAHRS)-sponsored workshop on cicatricial alopecia, Duke University Medical Center, February 10 and 11, 2001.
        J Am Acad Dermatol. 2003; 48: 103-110
        • Kossard S.
        • Lee M.
        • Wilkinson B.
        Postmenopausal frontal fibrosing alopecia: a frontal variant of lichen planopilaris.
        J Am Acad Dermatol. 1997; 36: 59-66
        • Headington J.
        Transverse microscopic anatomy of the human scalp. A basis for a morphometric approach to disorders of the hair follicle.
        Arch Dermatol. 1984; 120: 449-456
        • Poblet E.
        • Jiménez F.
        • Pascual A.
        • Piqué E.
        Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathologic study.
        Int Soc Dermatol. 2006; 45: 375-380
        • Nambudiri V.E.
        • Vleugels R.A.
        • Laga A.C.
        • Goldberg L.J.
        Clinicopathologic lessons in distinguishing cicatricial alopecia: Seven cases of lichen planopilaris misdiagnosed as discoid lupus.
        J Am Acad Dermatol. 2014; 71: e135-e138