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Assessment of biotin supplementation among patients in an outpatient dermatology clinic

Published:January 07, 2019DOI:https://doi.org/10.1016/j.jaad.2018.12.045
      To the Editor: Biotin, or vitamin B7, is essential for metabolic pathways, but supplementation is unnecessary for patients who are following a normal Western diet and do not have any malabsorption issues or nutrient deficiencies.
      Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate OBV and C
      Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.
      Although there is limited evidence that biotin supplementation improves skin, hair, and nail conditions, it is routinely recommended by dermatologists and primary care physicians.
      • Lipner S.R.
      Rethinking biotin therapy for hair, nail, and skin disorders.
      • Lipner S.R.
      • Scher R.K.
      Biotin for the treatment of nail disease: what is the evidence?.
      • Patel D.P.
      • Swink S.M.
      • Castelo-Soccio L.
      A review of the use of biotin for hair loss.
      A recent US Food and Drug Administration warning stated that biotin supplementation can interfere with laboratory tests, potentially leading to missed or inappropriate diagnoses with clinical implications.
      US Food and Drug Administration
      The FDA warns that biotin may interfere with lab tests: FDA safety communication.
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      References

        • Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate OBV and C
        Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline.
        National Academies Press, Washington, DC1998https://doi.org/10.17226/6015
        • Lipner S.R.
        Rethinking biotin therapy for hair, nail, and skin disorders.
        J Am Acad Dermatol. 2018; 78: 1236-1238
        • Lipner S.R.
        • Scher R.K.
        Biotin for the treatment of nail disease: what is the evidence?.
        J Dermatolog Treat. 2018; 29: 411-414
        • Patel D.P.
        • Swink S.M.
        • Castelo-Soccio L.
        A review of the use of biotin for hair loss.
        Skin Appendage Disord. 2017; 3: 166-169
        • US Food and Drug Administration
        The FDA warns that biotin may interfere with lab tests: FDA safety communication.